They take quite a few hits from weapons, so ranged weapons are most recommended. When killed, their corpses will either be destroyed or they will fall to the ground. If they fall to the ground, they can be taken under control by the Octomators. Once possessed, they are faster and can evade/block Dan's attacks. To prevent this, the Hammer, Pistol, Blunderbuss, or Gatling Gun should be used to destroy their corpses.